What's the require to start this course

do I have to now react and node.js to start this course?

No, not react or node specifically, but you must know the basic javascript programming concepts.

In the first few lecture you will see:

In order to run properly, the MFlix software project has some installation requirements and environmental dependencies.

These requirements and dependencies are defined in this lesson, and they can also be found in the README.rst file from the mflix-js handout. This lesson is to make sure you don’t skip them!

After following this README, you should be able to successfully run the MFlix application.

Just follow the instructions and it should work. Downloading the dependencies is part of the instructions that you will have to follow.